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特殊氨基酸
特殊氨基酸及其衍生物是设定多肽的重要工具。将特殊修饰氨基酸用于多肽合成,昂拓莱司在此领域具备丰富的经验,包括N-甲基氨基酸、D-型氨基酸、β-氨基酸、γ-氨基酸等其他众多非天然氨基酸及衍生物。
{Aib} | |
---|---|
{Abu} | {Cys(Acm)} |
{D-Abu} | {D-Cys(Acm) |
{Beta-Asp} | {Cys(tBu)} |
{D-Beta-Asp} | {Cys(StBu)} |
{Cit} | {Cys(Nitosothiols)} |
{D-Cit} | {Cys(Pyrene-Maleimide)} |
{Cpg} | {Met(O)} |
{D-Gamma-Glu} | {Tyr(Et)} |
{Hyp} | {D-Tyr(Et)} |
{Nva} | {Lys(Ac)} |
{D-Nva} | {Lys(Dde)} |
{Nle} | {Gly(allyl)} |
{D-Nle} | {D-Gly(allyl)} |
{Phg} | {Ser(Octanoic acid)} |
{D-Phg} | {D-Ser(Octanoic acid)} |
{Tle} | {Ser(Lipoic acid)} |
{Arg(Me)2} | {3-Ala(2-thienyl)-OH} |
Symmetrical | {3-Ala(3-thienyl)-OH} |
{Arg(Me)2} | {N-Me-Ala} |
Asymmetrical | {N-Me-Asp} |
{Arg(Me)} | {N-Me-Glu} |
{Cys(Me)} | {N-Me-Gly} |
{Thr(Me)} | {N-Me-Leu} |
{Ser(Me)} | {N-Me-Met} |
{Lys(Me)} | {N-Me-Ile} |
{Lys(Me2)} | {N-Me-Nle} |
{Lys(Me3)} | {N-Me-Nva} |
{Orn(Me)3} | {N-Me-Phe} |
{Tyr(Me)} | {N-Me-Ser} |
{L-1-Me-Trp} | {N-Me-Thr} |
{L-2-Me-Trp} | {N-Me-Tyr} |
{D-2-Me-Trp} | {N-Me-Val} |