β-amyloid (1-16)
添加购物车名称 | β-amyloid (1-16) |
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CAS No. | 131580-10-4 |
目录号 | ONP10824 |
规格 | mg/g |
纯度 | ≥98% |
价格 | 更多在线询价 |
贮存 | -20°C |
分子量 | 1955.02 |
序列结构 | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH |
库存 | |
产品简述 | Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Beta-amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer’s disease with Beta-amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage. |